6 common drugs that increase your risk of heart failure, according to a pharmacist

6 common drugs that increase your risk of heart failure, according to a pharmacist

6 common drugs that increase your risk of heart failure, according to a pharmacist

Your heart is one of the most central organs in your body, the master force that controls the flow of blood that affects every other organ and system. Full lifestyle choices can help keep your heart healthy in good working orderincluding a healthy diet and regular exercise. Some people may also take certain medications, like statins or anticoagulants to help their heart work as it should.

Many factors can contribute to potential heart failure, including certain medications that are commonly used to treat other diseases and conditions, and this is especially true if you have a history of heart problems. Christine CadizPharmD said Best life which drugs can increase your risk of heart failure. Read on to find out what they are.

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6 common drugs that increase your risk of heart failure, according to a pharmacist

People with heart failure should avoid taking nonsteroidal anti-inflammatory drugs (NSAIDs) sold under brand names such as Advil, Aleve and Motrin, Cadiz explains. “All NSAIDs, such as ibuprofen and naproxen, may increase the risk of heart failure exacerbation (or acute worsening of heart failure) and hospitalization.”

NSAIDs can also cause blood pressure to rise by constricting and dilating the blood vessels in your body. Not to mention, “when combined with other medications commonly used to treat heart failure, NSAIDs also increase the risk of kidney toxicity,” Kadis says.



Aspirin is another NSAID that can also be used as a blood thinner and to treat inflammation, headaches, pain and fever. According to Cadiz, this drug “should be avoided in high doses used to treat pain and inflammation, although low-dose aspirin used for cardiovascular protection is generally okay.”

Heart failure can occur because high doses of aspirin can cause sodium retention, which then leads to excess water in the body. “Too much fluid in the body leads to symptoms such as swelling in the legs, bloating, congestion in the lungs, which makes breathing worse, and also makes it harder for your heart to pump enough blood around the body. “, he explains.

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“Pseudoephedrine [the active ingredient in Sudafed] constricts the blood vessels in the nose and sinuses,” explains Harvard Health. “This reduces swelling and drains fluids, allowing you to breathe more easily again. Unfortunately, the drug does not only affect the head, it stretches the blood vessels whole body.”

Caddis says this stretch “can cause cardiotoxicity, especially at higher doses or with long-term use.” This means that Sudafed and other decongestants may increase the risk of hospitalization and heart failure in people with existing heart problems. These drugs “should be avoided in patients with heart failure or any cardiovascular disease,” he warns.


Vitamin E

Although humans need healthy doses of vitamins and minerals to survive, it is a known fact that it can be; it is risky to take too much any addition. Cadiz says dietary supplements can cause unwanted results in patients who have underlying conditions or who are taking other medications.

“Recently published research European Journal of Heart Failure found that vitamin E supplementation was associated with a modest but significant increase in heart failure hospitalizations, although the reason for this is unclear,” he says. “Based on the results, the authors of the study concluded that vitamin E may worsen patient outcomes. with pre-existing heart failure,” but fortunately did not increase the risk of developing heart failure.

“As with any medication, it is recommended to evaluate the risks and benefits of therapy before starting supplementation,” he says. “Also, it’s important not to take more than the recommended daily allowance.”

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Some diabetes medications

About one in 10 Americans suffers from diabetes, according to the Centers for Disease Control and Prevention (CDC). This disease is a chronic health condition that affects how your body converts food into energy. For patients with diabetes, it is difficult for the body to prepare and insulin regulationwhich leads to high blood sugar and leads to a host of other health problems.

Cadiz explains that several diabetes medications should not be used by patients with a history of heart failure. “These are known as thiazolidinediones (TZDs), such as pioglitazone (Actos) and rosiglitazone (Avandia, now discontinued in the US). These agents can cause fluid retention and can worsen heart failure.”

Fortunately, there is some good news when it comes to these drugs and your heart. “Not all diabetes medications are harmful in heart failure,” Kadis notes. “There are actually specific medications for diabetes that have been shown to be very helpful in heart failure, which are SGLT2 inhibitors (empagliflozin is known as Jardiance and dapagliflozin is known as Farxiga).


Some cancer-fighting drugs

“There have been many advances in cancer treatment in recent decades,” Kadis says. “Unfortunately, some of the most effective cancer-fighting drugs can be associated with serious heart complications. Certain cancer drugs are known to carry an increased risk of chemotherapy-induced cardiotoxicity, leading to symptoms of heart failure due to reduced left ventricular output. fraction, or a decrease in the heart’s ability to contract effectively to pump blood around the body.”

The drugs most commonly associated with cardiovascular toxicity are anthracyclines, including doxorubicin, idarubicin, and daunorubicin. The more you take these medications, the greater your risk of developing heart failure. “Because anthracyclines and other chemotherapy agents increase the risk of heart failure and other cardiovascular complications, in recent years there has been a growing field of research and practice called cardio-oncology aimed at treating and preventing cardiotoxicity from cancer therapy,” Kadis explains. :

Best Life offers the most up-to-date information from top experts, new research and health agencies, but our content is not a substitute for professional guidance. When it comes to medications you take or other health questions you have, always contact your healthcare provider directly.

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