Wegovy makes people averse to their favorite foods and drinks
Revolutionary weight loss drug Wegovy causes users to hate the taste of their favorite treats.
Americans prescribed a once-a-week injection say they have suddenly become averse to coffee and certain sweets and fast food.
Wegovy and its sister drug Ozempic, which use the active drug semaglutide, work by replicating the hormones that tell the brain it’s full.
These hormones are supposed to make a person feel full and reduce the desire for food. But for people like Staci Rice, 40, of Georgia, they have ruined some of their simple pleasures in life.
Ms. Rice had been drinking coffee every day since the seventh grade before using Wegovy to lose 50 pounds in six months. Now he can’t hold the cup.
She said Informed two of her past favorite treats, a fried chicken sandwich from Chic-fil-A and Kit-Kat bars, have also become repulsive to her.
Kait Morris, a TikToker with more than 6,000 followers, said she can no longer eat a full plate of food and only wants smoothies after using drugs.
Reddit users on a forum dedicated to discussing the drug are also complaining that they can no longer eat their favorite snacks, with one even saying that all food now tastes “yuck”.
Experts say these taste disturbances occur because the drug changes the brain’s ability to tell what is going into a person’s mouth – causing a taste disorder called dysgeusia.
The condition causes certain foods and drinks to appear sweet, sour, bitter or metallic.
Wegovy has become a highly sought-after drug since it first became available in the US last year. In clinical trials, it has shown the ability to reduce a person’s body weight by about 15 percent over 68 weeks.
Famous users include Elon Musk, who credited Wegovy for his body transformation on Twitter. Kim Kardashian is also rumored to have used injections.
Staci Rice (left), 40, said she could no longer digest coffee or Kit-Kats after using Wegovy. Kait Morris (right) said Ozempic hurt her relationship with food. Her problems with taste have since passed, she said
Mrs Rice (pictured) has lost 50 pounds on Wegovy after using it for the past six months
Wegovy is a GLP-1 drug that has been heralded for its value as a weight loss supplement.
‘Every morning I would try to make coffee, thinking that one day it would be good again,’ said Ms Rice.
She was also a fan of the “No. 1” meal at Chic-fil-A, a 440-calorie fried chicken sandwich with 1,400 grams of sodium and 6 grams of sugar.
The meal no longer appeals to her, and the kale salad from the fast food chain is now her choice.
Kit-Kats, which she says used to be her favorite Halloween treat, taste indescribably bad to her. Now all chocolate is tasteless to her.
She also can’t digest ground beef, so she removes it from dinner at home much to her husband’s chagrin.
WHAT IS WEGOVY?
Wegovy is the brand name for a drug called semaglutide.
A 1mg dose of semaglutide is already approved in the UK as a treatment for people with type 2 diabetes.
But studies have found that 2.4 mg of the drug works effectively as a weight loss drug.
It works by stimulating the body to produce a hormone called glucagon-like peptide-1 that is naturally released from the gut after eating.
The hormone helps control blood sugar and makes people feel full so they know when to stop eating.
The results of research on 2,000 people over 15 months show that the participants lost an average of 15 percent of their body weight, which is 15.3 kg.
Along with weekly injections, the group received individual counseling from registered dietitians to help them stick to a low-calorie diet and exercise plan.
Volunteers reported improved quality of life and reduced risk factors for developing heart disease and diabetes, such as reduced waist circumference, blood fat, blood sugar and blood pressure.
But drug-induced side effects include mild to moderate nausea and diarrhea, but the researchers say these were short-lived and resolved on their own.
Semaglutide is a glucagon-like peptide-1 (GLP-1) drug that mimics the effects of a hormone that is naturally produced in a person’s stomach and pancreas.
These hormones signal the brain not to eat. This reduces the person’s appetite and reduces the desire for food.
It also slows gastric emptying and increases the amount of insulin secreted by the pancreas.
Ozempic, the first drug formulation produced by Novo Nordisk, was originally designed to help diabetics manage their condition.
However, those who used the drug also experienced significant weight loss.
This led the Danish company to reformulate the drug into Wegovy, which is approved for weight loss.
Common side effects of the drug include nausea, diarrhea, and other gastrointestinal problems.
It is used by weekly injection in the thigh, arm or abdomen.
Some users report symptoms like Ms. Rice’s, however, where their relationship with food is significantly altered.
Ms Morris has thousands of followers on her TikTok account where she discusses her use of Ozempic and shares updates on her weight loss journey.
‘I miss eating. I miss going out to restaurants. I miss ordering a normal plate of food,’ she said during a video released in September.
She also said that she can no longer eat meat and now only wants smoothies.
During a video posted on October 14, Ms Morris said she skipped her weekly injection because some of her side effects were ‘really intense’. She added that she is still committed to filming the weekly shoot.
During the nine months she used the medicine, she lost 65 kilograms.
Ms Morris also added during a video released last week that she was doing ‘very well’ with the food as some of her side effects had subsided.
On the Reddit forum r/Ozempic, users highlighted their food struggles stemming from drug use.
‘Ozempic seems to have changed my palate. Suddenly everything tastes like…yuck,’ one user wrote in a thread over the summer.
‘…Especially meat. It tastes very bad to me, and I used to like meat. The thought of steak now makes me nauseous. I used to love food — I rarely ate anything I didn’t like. The taste is just… bad.
‘Sweet things are much too sweet – almost repulsive. The only thing that still tastes good is fruit and sour which I crave like never before.’
Another user said they ‘miss the enjoyment’ of food because they don’t enjoy eating now.
‘Food is disgusting to me too. Eating is just weird. Either I’m starving and everything is gross or I’m sick to my stomach and can’t eat,’ said another Reddit user.
Due to the relatively new nature of this class of drugs, there is no research available on how they affect the brain in a way that impairs taste.
Sr. Ed Walker, chief scientist at New Zealand government-funded Plant & Food Research, told DailyMail.com it could be related to the way the drug is taken.
Since the injections are taken once a week, the body will have days where the levels of the GLP-1 hormone are significantly increased.
This is unnatural – because the body releases hormones only as much as they are needed. The resulting hormonal imbalance can lead to strange side effects such as a change in taste.
dr. Lynnette McCluskey, a professor of neuroscience at Augusta University in Georgia, told Insider that the altered signals mess with the human brain.
“Once you start messing with all those signals — and they can be different from day to day, or when you’ve taken a drug — you really have a lot of potential for dysgeusia or a taste disorder,” she said.
Ozempic helps overweight children reduce their BMI by almost a FIFTH
A repurposed diabetes drug given once a week could reduce an obese child’s weight by almost a fifth, research has found.
Adolescents aged 12 to 17 who received semaglutide – brand name Wegovy – lost an average of 14 percent of their body weight in 16 months.
That translated to 16 percent of their body mass index (BMI), a measure of body fat based on height and weight. One in four losers reduced their BMI by a fifth.
In comparison, a control group given diet and exercise advice gained 2.4 percent more weight over the same period, and their BMI increased by 0.6 percent.
University of Minnesota researchers who led the trial said the drug was ‘the most effective anti-obesity drug for teenagers’ to date.
Participants came to them ‘in tears’ because they were so pleased with the results, and one participant said that the medicine made her ‘feel better in her own skin’.
The scientists hope their results will ensure the Food and Drug Administration (FDA) approves the drug for use in children, opening other avenues for weight loss.
The US is in the midst of a childhood obesity epidemic, with one in five teenagers already considered obese, or 14.7 million people.
increases the risk of conditions later in life including diabetes and heart disease.
Wegovy — which stimulates areas of the brain that help people feel full after eating — is currently only approved for adults 18 and older in the US.
One weight-loss injection — liraglutide — is approved for use in children, but must be given once a day.